JRM
Journal of Radiology in Medicine

Journal of Radiology in Medicine is an international journal that published original research and articles in all areas of radiology. Its publishes original research articles, review articles, case reports, editorial commentaries, letters to the editor, educational articles, and conference/meeting announcements.

eISSN: 3023-6487
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Original Article
Haemodynamic effects of carotid artery stenting on cerebral perfusion: a CT perfusion study
Abstract
Aims: To evaluate cerebral haemodynamic changes using computed tomography perfusion (CTP) imaging before and after carotid artery stenting in patients with significant internal carotid artery (ICA) stenosis.
Methods: This retrospective study included 34 patients with unilateral ICA stenosis who underwent carotid angiography and were considered candidates for endovascular treatment. Cerebral perfusion CT examinations were performed using a 64-detector CT scanner before carotid artery stenting. In 14 patients with marked perfusion abnormalities, follow-up perfusion CT examinations were also performed after stent placement. Cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT) values from the affected hemisphere were compared with those of the contralateral normal hemisphere. Pre-treatment and post-treatment perfusion parameters were also analysed using GE Perfusion 4 software. Statistical significance was accepted at p<0.05.
Results: Among the 34 patients, increased CBV and CBF values were detected in the stenotic hemisphere in 27 patients, while prolonged MTT values were observed in 28 patients. In the subgroup of 14 patients who underwent post-stenting perfusion evaluation, significant improvement in cerebral perfusion parameters was demonstrated after carotid artery stenting. Following treatment, MTT values decreased, indicating shortened cerebral transit time and improved haemodynamics. Significant differences were observed between pre-treatment and post-treatment perfusion measurements (p<0.05). These findings suggest restoration of cerebral perfusion after revascularisation therapy.
Conclusion: Carotid artery stenosis significantly affects cerebral perfusion, and carotid artery stenting contributes to improvement in cerebral haemodynamics. Computed tomography perfusion imaging is a valuable and non-invasive technique for evaluating cerebral perfusion abnormalities, determining treatment timing, and assessing post-treatment haemodynamic recovery in clinically stable patients with carotid artery stenosis.

Keywords : Carotid stenosis, carotid artery stenting, cerebral blood flow, perfusion imaging, ischaemic stroke

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Article available in :
Volume 3, Issue 2, 2026
Page : 28-32
https://doi.org/10.51271/JRM-0046
Article Information
Received : 01 May 2026
Accepted : 09 Haz 2026
Published : 29 Haz 2026
Corresponding Author :

Ayhan Duman: Department of Radiology, Gaziantep Medicalpoint Hospital, Gaziantep, Turkiye

[email protected]
Citation : Duman A, Şirikci A. Haemodynamic effects of carotid artery stenting on cerebral perfusion: a CT perfusion study. J Radiol Med. 2026;3(2):28-32. doi:10.51271/JRM-0046

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