JRM
Journal of Radiology in Medicine

Journal of Radiology in Medicine is an international journal that published original research and articles in all areas of radiology. Its publishes original research articles, review articles, case reports, editorial commentaries, letters to the editor, educational articles, and conference/meeting announcements.

eISSN: 3023-6487
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Online Manuscript System

Index
Original Article
Evaluation of the relationship between prostate volume and prostate specific antigen in patients diagnosed with benign prostatic hyperplasia
Abstract
Aims: The aim of this study was to investigate the relationship between prostate volume and prostate specific antigen (PSA) levels in patients diagnosed with benign prostatic hyperplasia (BPH). In addition, it is aimed to show that BPH may be one of the causes of PSA elevation in patients without prostate cancer.
Methods: Prostate volume was calculated in 60 BPH patients who underwent prostate magnetic resonance imaging (MRI) imaging in radiology department between December 1, 2023 and March 1, 2024 due to elevated PSA. The relationship between prostate volume and the tpsa and fpsa values of the patients in the last month was evaluated.
Results: There was a positive correlation between age and total prostate specific antigen (tpsa) and free prostate specific antigen (fpsa) in patients with benign prostatic hyperplasia. However, the correlation between age and fpsa was stronger. Similarly, a positive correlation was found between prostate volume and tpsa and fpsa. The correlation between increased prostate volume and increased fpsa was also stronger.
Conclusion: In our study, a positive correlation was found between prostate volume and tpsa and fpsa in patients diagnosed with BPH. It was determined that one of the reasons for the increase in PSA values may be the increase in prostate volume.

Keywords : Benign prostatic hyperplasia, prostate specific antigen, prostate volume, magnetic resonance

Download Article


1. Akang EE, Aligbe JU, Olisa EG. Prostatic tumours in Benin City,Nigeria. West Afr J Med. 1996;15(1):56-60.
2. Egan KB. The epidemiology of benign prostatic hyperplasia associatedwith lower urinary tract symptoms: prevalence and incident rates. UrolClin North Am. 2016;43(3):289-297.
3. Nwafor CC, Keshinro OS, Abudu EK. A histopathological study ofprostate lesions in Lagos, Nigeria: a private practice experience. NigerMed J. 2015;56(5):338-343.
4. Boyle P, Napalkov P. The epidemiology of benign prostatic hyperplasiaand observations on concomitant hypertension. Scand J Urol NephrolSuppl. 1995;168:7-12.
5. Roehrborn CG. The epidemiology of acute urinary retention in benignprostatic hyperplasia. Rev Urol. 2001;3(4):187-192.
6. Catalona W, Richie J, Ahmann FR, et al. Comparison of digital rectalexamination and serum prostate specific antigen in the early detectionof prostate cancer: results of a multicenter clinical trial of 6,630 men. JUrol 1994;151(5):1283-1290.
7. Nnabugwu II, Ugwumba FO, Enivwenae OA, Udeh EI, Otene CO,Nnabugwu CA. Serum total prostate-specific antigen values in menwith symptomatic prostate enlargement in Nigeria: role in clinicaldecision-making.Clin Intervent Aging. 2015;10:89-93.
8. Mao Q, Zheng X, Jia X, et al. Relationships between total/freeprostate-specific antigen and prostate volume in Chinese menwith biopsy-proven benignprostatic hyperplasia. Int Urol Nephrol.2009;41(4):761-766.
9. Mosli H, Abdel-Meguid TA. The relationship between prostate volume,Prostate-specific antigen and age in Saudi men with benign prostaticconditions. Afr J Urol. 2010;16(4):117-123.
10. Udeh E, Dakum N, Amu O, Ramyil V. Correlation between serumprostate specific antigen and prostate volume in Nigerian men withbiopsy proven benign prostatic hyperplasia:(A prospective study).Internet J Urol. 2009;7(2):10-5580.
11. Aigbe E, Irekpita E, Ogbetere FE, Alili UI. Correlation between prostatevolume and prostate-specific antigen in Nigerian men with symptomatichistologically-diagnosed benign prostatic hyperplasia.Nigerian J ClinPract.2022;25(9):1523-1528.
Article available in :
Volume 1, Issue 2, 2024
Page : 20-22
https://doi.org/10.51271/JRM-0006
Article Information
Received : 27 Mar 2024
Accepted : 23 Nis 2024
Published : 27 Nis 2024
Corresponding Author :

Alper Göncüoğlu: Department of Radiology, Konya Numune Hospital, Konya, Turkiye

[email protected]
Citation : Göncüoğlu A, Göncüoğlu C, Günay İ. Evaluation of the relationship between prostate volume and prostate specific antigen in patients diagnosed with benign prostatic hyperplasia . J Radiol Med. 2024;1(2):20-22.

Read: 793
Cited: 0
Download : 175
_Footer